As an epidemiologist and implementation scientist, I am passionate about enhancing global health equity with clear programmatic and policy implications for vulnerable populations, particularly those who engage in sex work and people who use drugs. My research examines intervention and policy impacts on the interrelationships among substance use (e.g., drugs and alcohol), stigma, and HIV/HCV/STI. I have had to privilege to work within Malawi, Vietnam, Ukraine, Thailand, Cameroon, and the Democratic Republic of Congo (DRC). In 2017, I launched the Substance Use Working Group within the International Epidemiological Databases to Evaluate AIDS (IeDEA) Network, where I serve as the Chair working with IeDEA regional representatives as well as program staff from NIAID, NIMH, NICHD, NIAAA, and NIDA, to generate real-world evidence on substance use and HIV policy and practice.